Beautiful After Breast Cancer Foundation

Prevention

Modern medicine is increasingly transitioning towards preventive care. This shift towards prevention has also been observed in breast cancer care in recent years, particularly with the discovery of the BRCA gene. Subsequently, multiple genes and risk factors have been identified. Depending on these factors, a personalized screening strategy can be chosen. Therefore, it is crucial to understand these genetic and risk factors.

Diagnosis

I was diagnosed with cancer ... This website serves as a portal designed to assist you and your loved ones in accessing personal information and finding solutions to your concerns.

The primary goal of this website is to offer guidance and support to patients as they navigate their journey toward recovery and improved quality of life. The "Diagnosis" section of our website is divided into two main categories. Firstly, under "Anatomy and Physiology," we provide fundamental knowledge about the breast. Secondly, in the "Tumors and Disorders" section, we delve deeper into various breast-related conditions.

Moreover, we aim to provide information to women who may be concerned about potential breast issues but are hesitant to seek immediate medical advice. Knowledge and information can often offer immediate reassurance if a woman is able to identify the issue herself and determine that no specific treatment is necessary. Conversely, we also strive to educate women who have received a diagnosis of a serious breast condition, such as breast cancer, and wish to approach their doctor well-informed and prepared.

Treatment

The treatment for breast cancer should immediately include a discussion about reconstruction. Our foundation has no greater goal than to raise awareness of this among patients and oncological surgeons. By making an informed decision beforehand, we avoid closing off options for later reconstruction while still considering the oncological aspect. Of course, survival is paramount, and the decision of the oncologic surgeon will always take precedence.

The "Reconstruction or not?" page contains all the information you can expect during an initial consultation before undergoing tumor removal. This page is comprehensive, and your plastic surgeon will only provide information relevant to your situation.

"Removing the tumor" details the surgical procedure itself. This is the most crucial operation because effective tumor removal remains paramount. We guide you through the various methods of removal, a decision often made by a multidisciplinary team comprising oncologists, radiologists, pathologists, radiotherapists, breast nurses, gynecologists, oncological surgeons, and plastic surgeons.

The "Breast Reconstruction" section includes information and illustrations of the different reconstruction options along with corresponding steps.

Revalidation

Those treated for cancer often need a long period to recover.

Cancer is a radical illness with a heavy treatment. Often, people have to deal with psychosocial and/or physical problems afterwards, such as stress, anxiety, extreme fatigue, painful joints, reduced fitness, lymphedema... This can have a major impact on general well-being.

There are rehabilitation programmes offered by most hospitals. We cover some of the major topics here.

Quality of life

Quality of life is a key factor in coping with breast cancer. Therefore, it is important to find coping mechanisms that work, which will be different from patient to patient. For some, it may be finding enjoyment in activities they engaged in prior to diagnosis, taking time for appreciating life and expressing gratitude, volunteering, physical exercise... Of prime importance, studies have shown that accepting the disease as a part of one’s life is a key to effective coping, as well as focusing on mental strength to allow the patient to move on with life. In this section we are addressing some topics that patients experience during and after treatment and we are providing information to address them.

Implants

Implants are essentially balloons mimicking the shape of a breast that can be placed underneath the skin or muscle of the chest wall (pectoral muscle). The outer layer of the balloon is usually made of silicone and the implant is filled with either silicone gel or a saline solution.

 

Timing

 

In an immediate implant reconstruction, the scar can be confined to the location of the areola, the implant placed through this access incision and the skin closed (Fig. 1). Later, using the same incision, a nipple reconstruction can be performed, limiting scarring.

Fig. 1: an immediate implant reconstruction performed by a central areolar incision only. The implant is placed in a pocket underneath the pectoral muscle

In a delayed implant reconstruction, the horizontal or diagonal mastectomy scar is already present and can be used to introduce the implant. Unfortunately though, the longer mastectomy scar remains visible (fig. 2). A delayed implant reconstruction can be done in one stage if there is sufficient overlying skin or if the breast is relatively small. In these instances, the prosthesis is immediately placed beneath the pectoralis major muscle. Usually, however, the reconstruction is performed in two stages.

Fig. 2: a delayed implant reconstruction after a modified radical mastectomy. The remaining skin needs to be expanded first and the expander replaced by a permanent sub-pectoral implant at a second procedure.

At the first operation, an expander is placed underneath the skin and muscle of the chest wall to stretch and create a pocket for the final prosthesis. An expander is an implant that is connected to a small subcutaneous valve, welded in the expander or placed at a distance and connected by a thin tube that can be punctured and filled with saline. This mechanism allows a gradual increase or decrease in the volume of the expander. In general, the purpose of an expander is to stretch the overlying skin near the chest wall and prepare it for a permanent prosthesis. The inflation begins approximately two to three weeks after the first operation. Every two weeks, the expander is filled, until it matches the size and volume of the other breast. Sometimes over-expansion is required to obtain a more natural breast shape. At the second procedure, the expander is removed and a permanent prosthesis inserted (Fig. 2).


A permanent expander can also be used. The procedure is the same as for a temporary expander but the device will not be replaced with a permanent prosthesis. This saves one operation but does not offer an opportunity for adjustment if the breast shape is less than ideal.

Implant types

Implants have dramatically improved over the last decade. The wall of the prosthesis used for reconstruction is now rough, so that it is less likely for an implant to move after surgery. Additionally, the devices are made in the shape of a pear or tear drop to mimic the shape of a natural breast. Instead of the traditional silicone gel, a cohesive gel is now used: if the shell of the prosthesis tears or breaks this gel will not spread elsewhere (Fig. 3), making the implants much safer.

Fig. 3: Most modern prostheses have a tear drop shape and are filled with a cohesive silicone gel.

Advantages of implant reconstruction

Implant based breast reconstruction is a relatively short, simple procedure with a low risk of postoperative complications; no additional scars are left on the body and the volume of the implants may be adjusted to the patient’s wishes, if expanders are used.

Disadvantages of implant reconstruction

The main drawback of implant based reconstruction is the high risk of late complications. Implants, like any medical device, are subject to wear and tear and eventually failure over time. The longer the prosthesis remains in situ, the higher this risk. Complications lead to further operations and ultimately a greater financial cost, when compared to autologous reconstruction.

Possible complications

1. Early complications

As with any surgical operation, bleeding, infection and wound healing problems are all possible. There is a slightly increased risk of infection with implants, as they are made of foreign material. Fluid collections around the implant, called seromas, can also often be detected following surgery.

2. Late complications

  • capsule formation and capsular contracture: capsular contracture is the most frequent late complication of implant based reconstruction and presents with firmness and deformation of the breast, with or without pain. Over time, the scar tissue surrounding an implant, which is soft and pliable in the beginning, may thicken and harden. As a general principle, the longer the implant remains in place, the higher the chances of this developing. A study by the FDA (Food and Drug Administration) in the United States has shown that the implants themselves are not responsible for any disease or illness but that repeated operations are the main cause of problems. As a result of this increased number of procedures, the total cost of implant based reconstruction is higher than autologous reconstruction. An implant reconstruction is estimated to last for 7 to 10 years.
  • wrinkling and rippling of the overlying skin
  • palpable implant edges
  • chronic pain
  • displacement or rotation of the implant
  • infections
  • leak, tear or rupture of the implant, caused by either trauma or material fatigue
  • necrosis of the overlying skin
  • siliconomas: these are less common now as the silicone gel is cohesive

There is however, no link between breast implants and auto-immune diseases, cancer, breast cancer recurrence, dermatological conditions or degenerative diseases.


In our experience and also according to the medical literature, administering radiotherapy, either before or after placing a breast implant, leads to a significant increase in all of these complications. In addition, later complications will develop earlier. The effects of radiotherapy can last for up to 15-20 years and as a result, many reconstructive centers no longer use implants in combination with radiotherapy.


Patients must also realize that it is frequently not possible to obtain the same excellent aesthetic results that can be achieved with autologous reconstruction, using implant based breast reconstruction.

Indications

Ideal candidates for implant based breast reconstruction are non-irradiated women with small non-sagging breasts. Good results can be achieved, particularly in bilateral reconstructions (fig. 4, 5). Patients who do not want additional scars elsewhere on their body or women with other associated medical problems that preclude a long surgical procedure (heart disease, coagulopathies, short life expectancy) are also potentially good candidates.


It is important to realise that implant reconstruction is not possible in patients in whom the entire pectoral muscle has been removed, the mastectomy skin flaps damaged or when severe radiation changes are present.

   
 Fig. 4a Fig. 4b 
 
 Fig. 4c Fig. 4d 
   
 Fig. 4e Fig. 4f 

Fig. 4: Pre-operative (a) and postoperative pictures of the same patient who underwent bilateral skin-sparing mastectomy with immediate reconstruction using expanders (b) and later exchange for permanent breast prostheses (c, d). The tattooing of the nipple reconstruction is initially dark but the color fades with time. (e) seven years and (f) nine years after the reconstruction,following rupture of the saline-filled right breast prosthesis.

 
 5a 5b 

Fig. 5: Pre-operative (a) and postoperative (b) pictures of a bilateral immediate implant breast reconstruction after areola-sparing mastectomies.

 

Evidence-Based Clinical Practice Guideline: Breast Reconstruction with Expanders and Implants

 

Read about breast reconstruction guidelines with implants in the following documents. These reports have been put together by a special guideline committee of the American Society of Plastic Surgeons (ASPS), using only data from sources and publications with a high degree of evidence based medicine (EBM). Breast reconstruction guidelines for autologous tissue will be available by the end of 2014.

Full versions:

 

References

 

Cronin TD, Gerow FJ. Augmentation mammaplasty: a new “natural feel” prosthesis. Transactions of the Third International Congress of Plastic and Reconstructive Surgery, Oct 13–18, 1963, Amsterdam, The Netherlands, Excerpta Medica Foundation, pp 41–49.

Cronin TD. Subcutaneuos mastectomy and gel implants. AORNJ. 1969;10:81-85.

Cronin TD, Upton J, McDonough JM. Reconstruction of the breast after mastectomy. Plast Reconstr Surg. 1977;59:1-14.

Radovan C. Tissue expansion in soft-tissue reconstruction. Plast Reconstr Surg. 1984;74:482-492.

Deapen DM, Pike MC, Casagrande JT, et al. The relationship between breast cancer and augmentation mammaplasty: An epidemiologic study. Plast Reconstr Surg. 1986;77:361.

Sanchez-Guerrero J, Coldiz GA, Karlson EW, et al. Silicone breast implants and the risk of connective-tissue disease and symptoms. N Engl J Med. 1995;332:1666-70.

Spear SL, Onyewu C. Staged breast reconstruction with saline-filled implants in the irradiated breast: recent trends and therapeutic implications. Plast Reconstr Surg. 2000;105(3):930-42.

Spear SL, Clack C, Howard MA. Postmastectomy reconstruction of the previously augmented breast: diagnosis, staging, methodology, and outcome. Plast Reconstr Surg.2001;107:1167.

Nahabedian MY, Tsangaris T, Moben B, et al. Infectious complication flowwing breast reconstruction with expanders and implants. Plast Reconstr Surg. 2003;112:467.

Salgarello M, Visconti G, Barone-Adesi L. Nipple-sparing mastectomy with immediate implant reconstruction: cosmetic outcomes and technical refinements. Plast Reconstr Surg. 2010;126(5):1460-71.

Jansen LA, Macadam SA. The use of AlloDerm in postmastectomy alloplastic breast reconstruction: part II. A cost analysis. Plast Reconstr Surg. 2011;127(6):2245-54.

Jansen LA, Macadam SA. The use of AlloDerm in postmastectomy alloplastic breast reconstruction: part I. A systematic review. Plast Reconstr Surg. 2011;127(6):2232-44.